Sci-Tech-Prod (Science-Technology-Products) Village: 科學技術產品村: 024
received from Pi-Twan Huang 黃碧端
文/陳曉莉 (編譯) 2007-09-12







Crospon執行長John O’Dea指出,由惠普所發明的、該產業第一個皮膚貼布可讓Crospon
Crospon Licenses HP Technology to Create Industry-first
Skin Patch for “Smart” Drug Delivery
received from Pi-Twan Huang 黃碧端
Fusion of high-tech and biotech improves safety, efficacy and ease-of-use for

PALO ALTO, Calif., Sept. 11, 2007

HP and Crospon, a medical device developer based in Galway, Ireland, today
announced they have entered a licensing agreement for a drug delivery platform that
enables painless, controlled release of one or more drugs in a single patch applied
to the skin.

Under the agreement, HP will license its intellectual property to Crospon in return
for royalty payments. Crospon will commercialize the patch, which was invented by
HP Labs, the company’s central research facility, and make it available to
pharmaceutical companies to use in various therapeutic areas.

Crospon, which recently announced the finalization of €2.3 million in seed financing,
will manufacture the skin patch and manage all marketing, sales and support of the

The patch delivers medication intradermally – just below the surface of the skin –
and enables precise control of dosage timing, access to dosage history, patient
activation mechanisms and inherent safety protocols for preventing adverse drug

Transdermal patches (which rely on absorption through the skin) for nicotine
delivery have become a mainstay for smoking cessation programs; however, they
have not been a widely effective delivery mechanism for many drugs because the
skin acts as a natural barrier.
The HP-developed skin patch uses microneedles that barely penetrate the skin; this radically reduces discomfort compared to traditional hypodermic needles and enables
the technique to be used with a much wider variety of drugs and biopharmaceuticals. The microneedles allow medication to quickly enter the bloodstream, resulting in the
potential delivery of lower and more precise dosages.

HP initially developed the drug delivery technology as a way to repurpose its inkjet technology for use in new markets. The technology in the skin patch is similar to that
employed in HP’s patented process for its inkjet cartridges.

“This industry-first skin patch invented by HP allows Crospon to offer a superior drug delivery platform for doctors and patients,” said John O’Dea, chief executive officer,
Crospon. “We look forward to working with our pharmaceutical customers to bring this breakthrough solution to the market.”

The agreement between HP and Crospon resulted in part from HP’s relationship with Enterprise Ireland, an Irish government agency tasked with supporting and growing
indigenous business in Ireland. Through Enterprise Ireland, companies can license the intellectual property of HP and access the company’s business and technology

“We encourage companies like Crospon to apply HP’s intellectual property in innovative ways to help more people benefit from these important technologies,” said Joe
Beyers, vice president, Intellectual Property Licensing, HP. “By licensing core intellectual property in thermal inkjet technology for use in a drug delivery product, HP breathes
new life into its mature technology while capitalizing on the booming healthcare and life sciences market.”

HP encourages other organizations worldwide to leverage its vast research and development network and portfolio of nearly 30,000 patents to bring new technologies to
market through intellectual property licensing agreements. These agreements also enable HP to generate a return on its R&D investment through licensing fees and

More information on HP’s intellectual property licensing program is available at

Images of the prototype drug delivery platform are available at

About Crospon

Crospon, formed in 2006, is a medical device company focused on the monitoring and treatment of diabetes and gastroesophageal reflux disorder (GERD). Crospon
recently announced the closure of a €2.3 million seed round of financing, which included investment by Enterprise Ireland and The Western Development Commission ( Company founder and Chief Executive Officer John O’Dea, previously co-founded Caradyne, a Galway, Ireland-based respiratory products company that
was acquired by Respironics Inc. in 2004.

About HP

HP focuses on simplifying technology experiences for all of its customers – from individual consumers to the largest businesses. With a portfolio that spans printing,
personal computing, software, services and IT infrastructure, HP is among the world’s largest IT companies, with revenue totaling $100.5 billion for the four fiscal quarters
ended July 31, 2007. More information about HP (NYSE: HPQ) is available at
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